Maodong Li

Center for Quantitative Biology, Peking University
Grad. 2013-2018
Research Area: Intrinsically disordered proteins
Email: bgalang_at_pku.edu.cn

Experiences:

1989.12, born in Shantou, Guangdong, China;

2009.9-2013.7, B. E. in Polymer materials and Engineering, School of Chemistry and Chemical Engineering, Sun Yat-Sen University;

2013.9-2018.7, Ph.D., Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University.

2018.7-2019.9： works in iCarbonX Inc. as a product manager.

2019.10-????: Shenzhen Bay Laboratory & Peking University Shenzhen Graduate School, postdoctor.

???-???: associate professor in Shenzhen Bay Laboratory

Publications:

1. Pengbo Song, Qiaojing Huang, Wenyu Li, Maodong Li* and Zhirong Liu*. Decomposition of forces in protein: Methodology and general properties. J. Chem. Inf. Model. 64 (18), 7108-7121 (2024).

2. Maodong Li, Huaiqing Cao, Luhua Lai, and Zhirong Liu. Disordered linkers in mutli-domain allosteric proteins: entropic effect to favor the open state or enhanced local concentration to favor the closed state? Protein Sci. 27 (9), 1600-1610 (2018).

3. Xuejiao Wang, Maodong Li, Pengbo Song, Xiaolin Lv, Zhirong Liu, Jianbin Huang, and Yun Yan. Reversible manipulation of supramolecular chirality using host-guest dynamics between β-cyclodextrin and alkyl amines. Chem. Eur. J. 24 (52), 13734-13739 (2018).

4. Luhao Zhang, MaoDong Li and Zhirong Liu. A comprehensive ensemble model for comparing the allostery of ordered and disordered proteins. PLOS Comput. Biol. 14 (12), e1006393/1-22 (2018).

5. Bin Chong, Maodong Li, Tong Li, Miao Yu, Yugang Zhang, and Zhirong Liu. Conservation of potentially druggable cavities in intrinsically disordered proteins. ACS Omega 3 (11), 15643-15652 (2018).

6. Chenyang Zhang, Maodong Li, Xuze Han, and Mingquan Yan. Quantum chemical examination of the sequential halogen incorporation scheme for the modeling of speciation of I/Br/Cl-containing trihalomethanes. Environ. Sci. Technol. 52 (4), 2162-2169 (2018).

7. Xiaoyun Zhang, Jian-Hua Wang, Dan Tan, Qiang Li, Maodong Li, Zhou Gong, Chun Tang, Zhirong Liu, Meng-Qiu Dong, and Xiaoguang Lei. Carboxylate-selective chemical cross-linkers for mass spectrometric analysis of protein structures. Anal. Chem. 90 (2), 1195-1201 (2018).

8. Maodong Li, Tanlin Sun, Fan Jin, Daqi Yu, and Zhirong Liu. Dimension conversion and scaling of disordered protein chains. Mol. Biosys. 12 (9), 2932-2940 (2016).

9. Maodong Li and Zhirong Liu. Dimensions, energetics and denaturant effects of protein unstructured state. Protein Sci. 25 (3), 734-747 (2016).

Meetings:

1. Maodong Li, Zhirong Liu. Denaturant effect on free energy of protein unfolding process. Poster. The 29th Chinese Chemical Society, Beijing, China, 2014.8.4-7.

2. Maodong Li, Zhirong Liu. Denaturant effect on free energy of protein unfolding process. Poster. The 11th National Conference of The Chinese Society of Biochemistry and Molecular Biology, Xiamen, China, 2014.8.21-23.

3. Maodong Li, Zhirong Liu. Dimensions, energetics and denaturant effects of the protein unstructured state. Poster. The 13th National Symposium of Computer & Computational Chemistry, Guangzhou, China. 2015.11.19-22.

4. Maodong Li, Tanlin Sun, Zhirong Liu. Coarse-grained Molecular Dynamics Simulations on Dimension Relationship of Disordered Protein Chains. Poster. The 30th Chinese Chemical Society, Dalian, Liaoning, China, 2016.6.30-7.4.

5. Maodong Li, Tanlin Sun, Fan Jin, Daqi Yu, and Zhirong Liu. Coarse-grained Molecular Dynamics Simulations on Dimension Relationship of Disordered Protein Chains. 7th KRIBB Asia-Pacific IDP Symposium. Oral. Daejeon, Korean, 2016.10.24-27.

6. Maodong Li, Huaiqing Cao, Zhirong Liu. The entropic effect of disordered linkers in allosteric regulation. Quantitative Biology 2017 International Conference. Oral. Beijing, China, 2017, 6.23-26.

7. Maodong Li, Huaiqing Cao, Zhirong Liu. The entropic effect of disordered linkers in allosteric regulation. 17th Asian Chemical Congress - Physical Chemistry. Oral. Melbourne, Australia, 2017.7.23-28.

Awards:

1. Outstanding Graduate of Peking University (2018.7).

2. National Scholarship for graduate students, Ministry of Eduation of the People's Republic of China (2017).

3. Peking University President Scholarship (2013, 2016).

4. Graduate student scholarship, Peking University (2015, 2016).

5. Graduate student scholarship of Quantitative Biology，second class, Peking University (2015, 2016).

6. Beijing-marathon, finished(2014, 2015, 2016, 2017), PB: 3 h 53 min 29s.

7. “Qicheng Cup” National Chess Champion Amateur Men's 4th, Amateur Team 1st, General Team 2nd (Peking University).

8. Peking University Graduate Chess Match, Champion (2013).

Hobbies:

Chess, Marathon, Novel.